Transformation of E. Coli with pUC8
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This led him to conclude that the _______cells must have been altered in some way by the material from the____ ______cells. Though the exact substance causing the change in the cells was unknown at the time, he proposed the some sort of __________caused the genetic exchange when two types of cells were combined. Years later, in the early 1940’s the work of Oswald Avery along with several colleagues, demonstrated exactly what the substance was that transformed cells. By isolating specific components from the __________ cells and exposing each component individually to the __________cells, it was demonstrated the only material that could cause transformation of the cells was____________. Their work was met with much skepticism initially because until that point it had been assumed that ___________ was the source of genetic material. However, repetition of the experiment and the work of several others proved conclusively that ______________ is indeed the transforming substance, as well as the source of genetic material