Ford Explorer running like two spark plugs are missing...?

[teran_realtor]

I have a 2003 Explorer. It suddenly started running real rough - like a couple spark plugs were out. I checked the wires to see if one had come off - not so easy! Went to Auto Zone and they checked the codes - sparks plugs misfiring and possible crankshaft position sensor. I changed all six plugs and then the sensor as well. Still runs the same. Any ideas?
I realized after I changed the sensor that I had not disconnected the battery before doing so - would this have killed the new one?

[jack1496t]

you should have replace the distributor cap and the rotor cap also replace the wire them could be cracked

[Justin]

It may be the ignition module or coil.

[wangsbuffet]

it sounds like your timing belt/chain went out or jumped depending on mileage you should definitely get it replaced